Accession Number : ADA299784

Title :   Human Immune Responses to Experimental Vaccinia Vaccines.

Descriptive Note : Annual rept.,

Corporate Author : MASSACHUSETTS UNIV MEDICAL CENTER WORCESTER

Personal Author(s) : Ennis, Francis A. ; Demkowicz, Walter E.

PDF Url : ADA299784

Report Date : 01 JUL 1995

Pagination or Media Count : 38

Abstract : Members of the U.S. Armed Forces receive immunization with vaccinia virus vaccine. Efforts to develop a safe and effective tissue culture-derived vaccinia vaccine to replace the standard vaccine produced by scarification on cows' skin have advanced early clinical studies. It is generally accepted that protection induced by the conventional vaccinia vaccine correlated with cellular immune responses. The I purpose of this research program is to measure human cellular and humoral immune responses to live experimental and standard vaccinia vaccines.

Descriptors :   *T LYMPHOCYTES, *VACCINES, *VACCINIA VIRUS, NUCLEAR PROLIFERATION, HUMANS, CLINICAL MEDICINE, RESPONSE(BIOLOGY), IMMUNOLOGY, IMMUNITY, CELLS(BIOLOGY), TEXAS, ANTIGENS, LYMPHOCYTES.

Subject Categories : Microbiology
      Medicine and Medical Research

Distribution Statement : APPROVED FOR PUBLIC RELEASE