Accession Number : ADA299826
Title : Development of Ligand-Transformed Alpha-Fetoprotein for Use Against Breast Cancer in Humans.
Descriptive Note : Annual rept. 1 Jul 94-30 Jun 95,
Corporate Author : ALBANY MEDICAL COLL NY
Personal Author(s) : Bennett, James A.
PDF Url : ADA299826
Report Date : 01 JUL 1995
Pagination or Media Count : 23
Abstract : Human alpha-fetoprotein (hAFP) upon incubation with sex steroid hormones is chemically converted into an inhibitor of estrogen-dependent breast cancer growth. This document describes the progress which was made during the first year of a research grant which was designed to develop the active form of hAFP as a treatment for breast cancer and establish markers which both predict and monitor breast cancer responsiveness to this form of AFP.
Descriptors : *PROTEINS, *CANCER, *MAMMARY GLANDS, *ESTROGENS, MAMMALS, MONITORING, HUMANS, GROWTH(GENERAL), ESCHERICHIA COLI, RESPONSE, INCUBATION, GENES, MICE, CELLS(BIOLOGY), CULTURES(BIOLOGY), RETARDATION, STEROIDS, SEX HORMONES.
Subject Categories : Anatomy and Physiology
Medicine and Medical Research
Distribution Statement : APPROVED FOR PUBLIC RELEASE