Accession Number : ADA299933

Title :   Chemical, Structural and Genetic Analysis of the Adhesive Holdfast of Biofouling Caulobacters.

Descriptive Note : Final rept. 1 Mar 89-28 Feb 94,

Corporate Author : BRITISH COLUMBIA UNIV VANCOUVER

Personal Author(s) : Smit, John

PDF Url : ADA299933

Report Date : 28 FEB 1994

Pagination or Media Count : 9

Abstract : This project was focussed on issues related to tne adhesion device used by marine and freshwater biofouling Caulobacter bacteria. The longterm goal of these studies was to improve our understanding of how fouling bacteria attach to surfaces and to consider potential strategies to prevent bacterial attachment to engineered surfaces. Progress on the four following OBJECTIVES during the course of the grant are reviewed: (1) Determination of the chemical composition and structural arrangement of monosaccharides and other substituents within the holdfasts of selected marine and freshwater Caulobacters. (2) Characterization of the types of surfaces to which holdfasts will adhere. (3) Cloning and analysis of the genes specifying the holdfasts of selected marine and freshwater Caulobacters. (4) Continuation of the development of capabilities for molecular genetic experimentation in a marine Caulobacter strain. (5) Evaluation of the occurrence, stability and behavior of Caulobacters on surfaces and in complex biofilms.

Descriptors :   *BACTERIA, *ADHESIVES, *BACTERIAL DISEASES, *FOULING ORGANISMS, *MONOSACCHARIDES, STRUCTURAL ANALYSIS, FILMS, CHEMICAL COMPOSITION, FRESH WATER, BIOLOGICAL CONTAMINATION, ORGANIC MATERIALS, CLONES, GENETIC ENGINEERING, GENETICS, RUBBER ADHESIVES.

Subject Categories : Biochemistry
      Genetic Engineering and Molecular Biology
      Microbiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE