Accession Number : ADA299943

Title :   Antibody-Based Detection of Toxins of Biological Origin.

Descriptive Note : Final rept. Oct 92-Sep 93,

Corporate Author : EDGEWOOD RESEARCH DEVELOPMENT AND ENGINEERING CENTER ABERDEEN PROVING GROUND MD

Personal Author(s) : Menking, Darrel E. ; Thompson, Roy G. ; Heitz, Jonathon M. ; Anis, Nabil A.

PDF Url : ADA299943

Report Date : SEP 1995

Pagination or Media Count : 22

Abstract : A Fiber optic evanescent fluorosensor was used to detect the presence of toxins of biological origin. A direct competition assay was used for cholera toxin and staphylococcus entertoxin B, and an indirect competition assay for cholera, botulinum toxoid A and ricin. Detection of toxins for both methods was in the nanomolar range.

Descriptors :   *FIBER OPTICS, *ENTEROTOXINS, *ANTIBODIES, *TOXINS AND ANTITOXINS, *STAPHYLOCOCCUS, *BACTERIAL TOXINS, DETECTION, RICIN, CHOLERA, CLOSTRIDIUM BOTULINUM.

Subject Categories : Microbiology
      Toxicology
      Fiber Optics and Integrated Optics

Distribution Statement : APPROVED FOR PUBLIC RELEASE