Accession Number : ADA299999

Title :   Prevention of Influenza and Other Respiratory Diseases.

Descriptive Note : Final rept. 1 Dec 89-31 Oct 94,

Corporate Author : COLORADO UNIV HEALTH SCIENCES CENTER DENVER

Personal Author(s) : Eickhoff, Theodore C. ; Meiklejohn, Gordon ; Levin, Myron

PDF Url : ADA299999

Report Date : 31 JAN 1995

Pagination or Media Count : 49

Abstract : This report presents the results of studies of influenza and influenza vaccines at Lowry AFB during the last 4 seasons, beginning in 1990-91, and concluding with the closure of Lowry AFB at the end of the 1993-94 season. The 1990-91 season was characterized by a moderate outbreak of influenza B; there was a late season outbreak of influenza A/H3N2 in the civilian community and at the Air Force Academy, but this was not seen at Lowry AFB. In the 1991-92 season, there were only a small number of cases of influenza A/H3N2 that occurred on base, although there was a moderate outbreak in the civilian community. There was a mixed outbreak of both influenza B and A/H3N2 during the 1992-93 season; the influenza A outbreak was apparent only in the permanent party; students were highly protected. During the 1993-94 season, although there was a significant outbreak of influenza A/H3N2 in the metropolitan Denver area, only a few cases were seen in permanent party and none in students at Lowry AFB. Current influenza vaccines are highly immunogenic and efficacious in young AF recruits and students when there is a good antigenic match of the vaccine strain with circulating strains; in older permanent party personnel, current vaccines are less immunogenic and clinical protection is incomplete. Continuing surveillance is necessary in order to detect emerging variants of influenza viruses.

Descriptors :   *CLINICAL MEDICINE, *INFLUENZA VIRUS, *RESPIRATORY DISEASES, *VACCINIA VIRUS, COMMUNITIES, STUDENTS, PROTECTION, ANTIBODIES, CIVILIAN POPULATION, PREVENTION, RECRUITS, VACCINES, UNITED STATES AIR FORCE ACADEMY, IMMUNOGENS.

Subject Categories : Microbiology
      Medicine and Medical Research

Distribution Statement : APPROVED FOR PUBLIC RELEASE