Accession Number : ADA300017
Title : Toxicity Assessment of Combustion Gases and Development of a Survival Model.
Descriptive Note : Final rept.,
Corporate Author : FEDERAL AVIATION ADMINISTRATION WASHINGTON DC OFFICE OF AVIATION RESEARCH
Personal Author(s) : Speitel, Louise C.
PDF Url : ADA300017
Report Date : JUL 1995
Pagination or Media Count : 140
Abstract : This report presents an extensive review of the literature on the toxic and thermal hazards relating to human survival in aircraft cabin fires. Studies by various authors of exposures to single and mixed gases on humans, primates, rats and mice are presented for different activity levels and a wide range of concentrations and temperatures. Regression equations giving the best fit were derived from these studies. The regression equation which was judged to best model the human escaping from an aircraft cabin fire was selected for each gas and utilized in the survival model. The effect of carbon dioxide increasing the uptake of other gases was included in the model. This survival model uses incapacitation data to obtain a fractional effective dose for incapacitation (FED1) and lethality data to obtain a fractional effective dose for lethality (FEDl). The time when either FED reaches 1 determines the exposure time available to escape from an aircraft cabin fire and to survive postexposure.
Descriptors : *THERMAL PROPERTIES, *TOXIC HAZARDS, *TOXICITY, *COMBUSTION PRODUCTS, EXPOSURE(GENERAL), HUMANS, SURVIVAL(GENERAL), GASES, REGRESSION ANALYSIS, LETHALITY, MIXING, PRIMATES, EQUATIONS, MICE, CARBON DIOXIDE, SURVIVAL(PERSONNEL), AIRCRAFT FIRES, INCAPACITATION, AIRCRAFT CABINS.
Subject Categories : Toxicology
Combustion and Ignition
Distribution Statement : APPROVED FOR PUBLIC RELEASE