Accession Number : ADA300298

Title :   Cytochemical Organization of the Retino-Suprachiasmatic System.

Descriptive Note : Final rept. 15 Dec 89-14 May 95,

Corporate Author : YALE UNIV NEW HAVEN CT DEPT OF NEUROSURGERY

Personal Author(s) : VAN DEN Pol, Anthony N.

PDF Url : ADA300298

Report Date : SEP 1995

Pagination or Media Count : 19

Abstract : Due to the support of the AFOSR Chronobiology Program, we have been very productive; in the past year (1994/1994) with about 25 papers completed. Many of these focus on amino acid transmitters in the SCN and surrounding area. We are pursuing the hypothesis that glutamate and GABA constitute two primary transmitters in the SCN, with glutamate exerting excitatory actions, and GABA exerting depressing actions in the adult SCN. We are using combinations of immunocytochemistry, electron microscopy, molecular biology, and patch clamp recording to study the SCN.

Descriptors :   *GLUTAMIC ACID, *NERVE CELLS, *CALCIUM COMPOUNDS, *IMMUNOLOGY, CHRONOBIOLOGY, CIRCADIAN RHYTHMS, CLOCKS, PERFORMANCE(HUMAN), CELLS, PEPTIDES, ELECTRON MICROSCOPY, MEMORY DEVICES, SHIFTING, TRANSMITTERS, MOLECULAR BIOLOGY, RECORDING SYSTEMS, WORK, HYPOTHESES, SALTS, MODULATION, ADULTS, AMINO ACIDS, CYTOCHEMISTRY, CLAMPS, JET LAG, ELECTRORETINOGRAPHY.

Subject Categories : Microbiology
      Biomedical Instrumentation and Bioengineering

Distribution Statement : APPROVED FOR PUBLIC RELEASE