Accession Number : ADA300586
Title : The Ventriculo-Arterial Coupling Ratio During Transient Gz Events,
Corporate Author : NORTH DAKOTA STATE UNIV FARGO
Personal Author(s) : Offerdahl, C. D. ; Ewert, D. L. ; Crisman, R. P. ; Convertino, V. A.
PDF Url : ADA300586
Report Date : 1995
Pagination or Media Count : 7
Abstract : It has been Shown by Westerhofet al. that the ratio tIT (where t = Rp *SAC and Rp is total peripheral resistance, SAC is systemic arterial compliance, and T is heart period) is approximately a constant in all mammals under resting conditions such that diastolic pressure is sufficiently high to assure adequate coronary perflision. The aim of this study is to determine if the ratio tIT is constant under the transient condition of a rapid onset rate +Gz acceleration. We hypothesize that the ratio is held constant by the cardiovascular control system. Four male baboons were subjected to 10 second rapid onset +Gz profiles and aortic pressure and flow were recorded. Rp and C were calculated using a 2-element windkessel model T was determined by the inverse of heart rate. All parameters were calculated on a beat-to-beat basis. It was found that the ratio increased very little at +2 (lz and increased dramatically at +3 and +5 Gz, disproving our hypothesis. This increase was due to large increases in peripheral resistance and changes in heart rate over the couse of a Gz run. The increases are presumed to represent baroreceptor reflex response to the drop in aortic pressure experienced during +Gz stress. The ratio tIT returned to its initial resting value shortly after the +Gz stressor was removed.
Descriptors : *ACCELERATION, *HEART RATE, *CARDIOVASCULAR SYSTEM, *RESISTANCE(BIOLOGY), TRANSIENTS, RATIOS, CONTROL SYSTEMS, MAMMALS, RESPONSE, PRESSURE, INVERSION, MALES, HYPOTHESES, SENSE ORGANS, COUPLINGS, AORTA, BLOOD PRESSURE, REFLEXES, BABOONS.
Subject Categories : Stress Physiology
Medicine and Medical Research
Distribution Statement : APPROVED FOR PUBLIC RELEASE