Accession Number : ADA300625

Title :   Gas Bubble Detection and Decompression Sickness Prevention by Noninvasive Bioelectrical Impedance Spectroscopy.

Descriptive Note : Final rept. Jan 87-Jun 90,

Corporate Author : DUKE UNIV MEDICAL CENTER DURHAM NC DEPT OF ANESTHESIOLOGY

Personal Author(s) : Gerth, Wayne A.

PDF Url : ADA300625

Report Date : MAY 1991

Pagination or Media Count : 233

Abstract : Excessively rapid decompression causee bubble formation in the blood and tissues which can in turn cause Decompreesion SicKness (DcS) through a var%ety of mecheniams that i%c1ude direct mechanical dama%e to tissue and perfusion impairment. %onjnvasive coniputer-driven Electrical %mpedance Spectroacopic (%IS) and Impedance Plet!%ys%ographic (IPG) methods were developed and used to track such bubble %ormation and it% attendant hernodynamic ef%ects. Studies Of bubble formation in gelatin confirmed theoretical in- dicatione that bubble formation and growth ahould cause systemtic changea in the alec- t%ical impedance spectr'n ot the hoct liquid throu%h e:fecte of a%lu%e adaor%tion at th bubble gaa liquid interface%. Using these changes as indices for b%bbLe formation in vi %IS technology was applied to detect bubble formation in the tails of rate decomprease to simulated altitudes. The tails were also roonitored for b%bble-in%%ced hemod%namic chan9es using more conventional IrG techniques. Results wsr% correleted with the in- cidence of DCS% which was %udged to have ocourred with the exhibition of re.piratory 0iatrees% convulajons or death. %ecauae the dacompressions used in theae animal experi- ments were 6%%%%5% further work remains to determine whet%er ZIS and IPG monitoring can provide noninvasive% ob%ectiva and preinonitory indices of DcS in man.

Descriptors :   *GASES, *BUBBLES, *BLOOD, *DECOMPRESSION SICKNESS, *ALTITUDE SICKNESS, SIMULATION, DETECTION, HIGH RATE, SPECTROSCOPY, INTERFACES, LIQUIDS, TAIL ASSEMBLIES, RATES, IMPEDANCE, DEATH, PREVENTION, GELATINS, BIOELECTRICITY.

Subject Categories : Stress Physiology
      Medicine and Medical Research

Distribution Statement : APPROVED FOR PUBLIC RELEASE