Accession Number : ADA302430

Title :   P53 Mutation Profiles in Premenopausal Versus Breast Cancer in a Stationary Population.

Descriptive Note : Annual rept. 1 Sep 94-31 Aug 95,

Corporate Author : SALK INST FOR BIOLOGICAL STUDIES LA JOLLA CA

Personal Author(s) : Yu, Bao-Fu

PDF Url : ADA302430

Report Date : SEP 1995

Pagination or Media Count : 12

Abstract : There is a difference in profiles of p53 mutation in pre and post menopausal breast cancers. Mutation of the p53 gene is often in exon 5 for postmenopausal breast cancer but mutation of p53 is often in exon 6 and 7 for premenopausal breast cancers, therefore p53 may be a useful epidemiological tool for identification of mutagen and genetic factors that contribute to breast cancer.

Descriptors :   *MUTATIONS, *MAMMARY GLANDS, *BREAST CANCER, TOOLS, POPULATION, STATIONARY, VIRUSES, GENETICS, EPIDEMIOLOGY, CANCER.

Subject Categories : Medicine and Medical Research
      Genetic Engineering and Molecular Biology

Distribution Statement : APPROVED FOR PUBLIC RELEASE