Accession Number : ADA303001

Title :   Low Molecular Weight Leachables From Medical Grade Polymers,

Descriptive Note : Final rept.,

Corporate Author : NATIONAL BUREAU OF STANDARDS GAITHERSBURG MD

Personal Author(s) : Howell, B. F. ; Chesler, S. ; Hilpert, L. ; Reeder, D. J.

PDF Url : ADA303001

Report Date : APR 1982

Pagination or Media Count : 35

Abstract : Four medically important polymeric materials (silicone polymer from mammary prostheses, polyurethane, polyethylene, and polycarbonate) were placed in contact with water for time periods ranging from four hours to seven days. Substances leaching into water were separated by extraction with methylene chloride, or by evaporation of water, and identification of species in the leachate was attempted by a number of analytical techniques, with extensive use of combined gas chromatography/mass spectrometry (GC/MS). Low molecular weight fragments of dimethylsiloxane were identified from mammary prosthesis gel. Spectra are also included for leachate from the other three polymers; identification of these compounds is still in process.

Descriptors :   *POLYMERS, *MOLECULAR WEIGHT, *LEACHING, *MEDICAL SUPPLIES, WATER, MATERIALS, IDENTIFICATION, MEDICINE, CHLORIDES, LIGHTWEIGHT, EXTRACTION, SEPARATION, EVAPORATION, METHYLENES, POLYURETHANE RESINS, POLYCARBONATES, FRAGMENTS, GAS CHROMATOGRAPHY, SILICONES, POLYETHYLENE, MASS SPECTROMETRY.

Subject Categories : Polymer Chemistry
      Medicine and Medical Research
      Physical Chemistry
      Laminates and Composite Materials

Distribution Statement : APPROVED FOR PUBLIC RELEASE