Accession Number : ADA303202

Title :   Statistical Methods for Analyzing Time-Dependent Events in Breast Cancer Chemoprevention Studies.

Descriptive Note : Annual rept. 30 Sep 94-29 Sep 95,

Corporate Author : STRANG CANCER PREVENTION CENTER NEW YORK

Personal Author(s) : Wong, George Y.

PDF Url : ADA303202

Report Date : OCT 1995

Pagination or Media Count : 48

Abstract : The overall aim of our research proposal is the statistical investigation of a non-parametric estimate which we call redistribution-to-the-inside estimator (RTIE) for the survival function s(t) = Pr(X > t), where the survival time X is subject to interval censoring. Our research efforts in the first year have been focused on two aspects of RTIE for interval censored data satisfying the condition that for any pair f censoring intervals, either they are disjoint, or one is a subset of the other (DI condition). First, we have completed the implementation of a computer program oded in the C language to carry out the RTIE estimation procedure, including a Kaplan-Meier type plotting program for RTIE written in the S+ language. Second, we derive the uniform almost sure limit (strong consistency) of RTIE for any arbitrary S and any arbitrary censoring distribution function C under the DI model.

Descriptors :   *COMPUTER PROGRAMS, *SURVIVAL(PERSONNEL), *CHEMOTHERAPY, *BREAST CANCER, TIME DEPENDENCE, PROGRAMMING LANGUAGES, STATISTICS, ESTIMATES, LIMITATIONS, LANGUAGE, STATISTICAL PROCESSES, DISTRIBUTION FUNCTIONS, CANCER, MAMMARY GLANDS, CENSORSHIP.

Subject Categories : Medicine and Medical Research
      Sociology and Law
      Escape, Rescue and Survival

Distribution Statement : APPROVED FOR PUBLIC RELEASE