Accession Number : ADA303779

Title :   Research Programs in Tropical and Infectious Diseases.

Descriptive Note : Annual rept. 11 Feb 94-30 May 95,

Corporate Author : HENRY M JACKSON FOUNDATION ROCKVILLE MD

Personal Author(s) : Bryan, Joe P. ; Laughlin, Larry ; Redington, Bryce

PDF Url : ADA303779

Report Date : 26 JUL 1995

Pagination or Media Count : 25

Abstract : During the period February 11. 1994-May 31. 1995 faculty and students at Uniformed Services University of the Health Sciences along with members of the staff of the Epidemiology Research Center in Belize accomplished five studies. A study of risk factors and social correlates of malaria among Mayan Indians in Belize who experience very high rates of malaria each year revealed that housing is not mosquito resistant. personal protective measures are not used, treatment was irregular, and reporting of malaria slide results is delayed. A one year study of hepatitis in Stann Creek district revealed the major etiologic agent of jaundice to be hepatitis B. Those with the highest incidence are Mayan Indians and Spanish speaking agricultural workers in the southern part of Stann, Creek district of Belize. A study of the seroprevalence of hepatitis B in school aged children in Stann Creek district indicated that the majority of children in two rural communities studied are exposed to hepatitis B before entering school while the prevalence of children in coastal towns is lower. A hepatitis B vaccine trial comparing three 5ug doses of Recombivax HB with two lO-ug doses was conducted among the Belize Defense Force: results are pending. A serologic study of Chagas' Disease was continued among blood donors: only 0.08% of blood donors had antibody to T. cruzi. Continued work with specimens from an outbreak of hepatitis in Pakistan revealed evidence of hepatitis E by serology or PCR for Hepatitis E in feces in 96% of 109 men hospitalized in the outbreak.

Descriptors :   *MALARIA, *INFECTIOUS DISEASES, *HEPATITIS, *TROPICAL DISEASES, PAKISTAN, COASTAL REGIONS, HIGH RATE, RISK, COMMUNITIES, EXPOSURE(GENERAL), STUDENTS, HEALTH, RESEARCH FACILITIES, RESEARCH MANAGEMENT, SEROLOGY, FECES, EPIDEMIOLOGY, CHILDREN, RURAL AREAS, CULICIDAE, MUNICIPALITIES, BLOOD DONORS, CHAGAS DISEASE.

Subject Categories : Medicine and Medical Research

Distribution Statement : APPROVED FOR PUBLIC RELEASE