Accession Number : ADA304212

Title :   Department of Clinical Investigation Annual Research Progress Report.

Descriptive Note : Rept. for 1 Oct 94-30 Sep 95,

Corporate Author : MADIGAN ARMY MEDICAL CENTER TACOMA WA DEPT OF CLINICAL INVESTIGATION

Personal Author(s) : Yeager, Curtis ; Patience, Troy ; Hough, Eugenia ; Jones, Barbara ; Whitten, Nancy

PDF Url : ADA304212

Report Date : 30 SEP 1995

Pagination or Media Count : 649

Abstract : In conducting the research described in this report, the investigators adhered to the 'Guide for the Care and Use of Laboratory Animals' as prepared by the Committee on the Care and Use of Laboratory Animals of the Institute of Laboratory Animal Resources, National Institutes of Health, and Title 9, Subchapter A, Parts I, II, and III of the Code of Federal Regulations. The investigators adhered to Title 21, Part 50 of the Code of Federal Regulations and the recommendations from the Declaration of Helsinki in the performance of investigations involving human subjects. In FY 95 the number of new protocols submitted and total protocols managed again reached a new high. During this FY, DCI processed 190 new protocols and manage 504 total protocols during the year. MAMC investigators continued to attract clinical trials at an increasing rate, augmenting their extramural funding through multiple foundations. MAMC nurses were again successful in competing for Tri-service Nursing research funding, bringing in over $250,000 in DOD nursing research funding. The department continued its strong thrust in molecular biology, training 1 fellows and staff in hands-on techniques and making progress in the areas characterizing wild-type and alternate SHBG mRNA transcripts in breast cancer (Dr. Kathy Moore), exquisitively sensitive detection of bacteria by PCR in amniotic fluid of pre-term deliveries (CPT Keith Martin), evaluating the presence of telomerase activity in multiple cancers (CPT Wade Aldous) and detection of bcl-2, bak and p53 gene products in therapeutically induced apoptosis in breast cancer cell lines (MAJ Rich Williams). jg

Descriptors :   *CLINICAL MEDICINE, UNITED STATES GOVERNMENT, DETECTION, BACTERIA, SENSITIVITY, CODING, RESOURCES, MOLECULAR BIOLOGY, CELLS(BIOLOGY), REGULATIONS, NURSES, PHARMACOLOGY, CANCER, MAMMARY GLANDS, LABORATORY ANIMALS, BREAST CANCER.

Subject Categories : Medicine and Medical Research
      Biology
      Medical Facilities, Equipment and Supplies

Distribution Statement : APPROVED FOR PUBLIC RELEASE