Accession Number : ADA304632

Title :   Injury Risk for Research Subjects With Spina Bifida Occulta in a Repeated Impact Study: A Case Review.

Descriptive Note : Final rept.,

Corporate Author : CANADIAN COMMERCIAL CORP OTTAWA (ONTARIO)

Personal Author(s) : Albano, John P. ; Shannon, Samuel G. ; Alem, Nabih M. ; Mason, Kevin T.

PDF Url : ADA304632

Report Date : JAN 1996

Pagination or Media Count : 12

Abstract : Spina bifida occulta (SBO) occurs in 18-34% of the normal U. S. population. Recently, 16.5% of normal, asymptomatic male soldier volunteer candidates in a U.S. Army Aeromedical Research Laboratory ride motion study were excluded from the study because they had SBO at one vertebral level. Disqualifying this percentage of screened research subject candidates threatened the timely completion of the schedule intense protocol. Although one study suggests that SBO at spinal level 51 has a higher incidence of posterior disc herniation, the preponderance of clinical literature reports that spina bifida occulta is not a medical problem. The impact literature indicates that lumbosacral vertebral bodies fracture at 7.14 kN in static compression and 20 plus g during dynamic vertical impacts. In this paper, we examined the human data observed in ejection seat incidents, the rationale for excluding volunteers with single level SBO, and the path of axial load transmission through the lumbosacral spine. Based on the findings, we concluded that research volunteers with single level SBO are not at increased risk for injury, and recommended inclusion of these volunteers in future studies involving repeated axial impacts due to ride motion.

Descriptors :   *WOUNDS AND INJURIES, *SPINAL COLUMN, *CONGENITAL ABNORMALITIES, *BONE FRACTURES, COMPRESSION, RATIOS, RISK, IMPACT, HUMANS, DYNAMICS, LOADS(FORCES), VOLUNTEERS, REPORTS, PATHS, MOTION, CLINICAL MEDICINE, POPULATION, MEDICINE, VERTICAL ORIENTATION, DOCUMENTS, AXES, EJECTION SEATS, MEDICAL RESEARCH, STATICS, AEROMEDICAL EVACUATION.

Subject Categories : Biology
      Anatomy and Physiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE