Accession Number : ADA304919

Title :   Directed Synthesis of New Antimalarials using Computer Aided Drug Design.

Descriptive Note : Final rept.,

Corporate Author : NORTH DAKOTA UNIV GRAND FORKS DEPT OF CHEMISTRY

Personal Author(s) : Avery, Mitchell A.

PDF Url : ADA304919

Report Date : 24 OCT 1995

Pagination or Media Count : 7

Abstract : This is a final report for a grant that was transfered, at the end of its first year, with the P.1. upon a change of Universities. Therefore, it encompasses only one year of work dealing with computer modeling of antimalarial drugs. We have developed a very reliable computer aided approach to defining the antimalarial activities of drugs related to the natural product, artemisinin.

Descriptors :   *COMPUTER AIDED DESIGN, *DRUGS, *ANTIMALARIALS, COMPUTERIZED SIMULATION, UNIVERSITIES.

Subject Categories : Pharmacology

Distribution Statement : APPROVED FOR PUBLIC RELEASE