Accession Number : ADA305658
Title : Effect of a Stress Reduction Intervention on Psycho-Immuno-Endocrine Parameters in Early Stage Breast Cancer.
Descriptive Note : Annual rept. 30 Sep 94-29 Sep 95,
Corporate Author : MASSACHUSETTS UNIV MEDICAL CENTER WORCESTER
Personal Author(s) : Massion, Ann O.
PDF Url : ADA305658
Report Date : 28 DEC 1995
Pagination or Media Count : 10
Abstract : The Breast Research Initiative for Determining Effective Skills for coping with cancer (BRIDGES) consists of a prospective, randomized intervention trial with 60 women in each of three arms (1) the UMass mindfulness mediation-based Stress Reduction and Relaxation Program (SR&RP); (2) a nutrition education program (NEP) developed specifically for BRIDGES; and (3) a usual care control group. The 180 women under age 65 with Stage I or Stage II breast cancer enrolling into this randomized trial are being evaluated for: (1) psychological and behavioral indices of function and coping (2) Quality of Life (QOL) measures, (3) compliance with the interventions and with medical treatment regimes, and (4) biochemical/immunological measures consisting of cytokines and melatonin. Analyses will be conducted to test hypotheses related to the three specific aims of the study. SR&RP effect on QOL; SR&RP & NEP effects on immune parameters, and durability/decay of intervention-related effects. As of 30 Sep 19, the study had closely adhered to the SOW agreed upon at the time the grant was awarded. Recruitment has achieved and is maintaining targeted levels. All subjects who have begun the study have been retained. All data has been collected.
Descriptors : *STRESS(PSYCHOLOGY), *STRESS(PHYSIOLOGY), *IMMUNOLOGY, *MEDICAL SERVICES, *PSYCHOLOGY, *MAMMARY GLANDS, *ENDOCRINOLOGY, *BREAST CANCER, TEST AND EVALUATION, STRESSES, CONTROL, EDUCATION, PARAMETERS, BIOCHEMISTRY, RANDOM VARIABLES, REDUCTION, QUALITY, INDEXES, RELAXATION, BEHAVIOR, HYPOTHESES, IMMUNITY, INTERVENTION, NUTRITION, BRIDGES, CANCER, LIVING STANDARDS, ENDOCRINE GLANDS, MELATONIN.
Subject Categories : Medicine and Medical Research
Distribution Statement : APPROVED FOR PUBLIC RELEASE