Accession Number : ADA305910

Title :   A Stochastic Approach to the Pharmacotherapeutic Management of Chronic Moderate Adult Asthma.

Descriptive Note : Master's thesis,

Corporate Author : NAVAL POSTGRADUATE SCHOOL MONTEREY CA

Personal Author(s) : Race, Lynda M.

PDF Url : ADA305910

Report Date : SEP 1995

Pagination or Media Count : 95

Abstract : This thesis demonstrates stochastic modelling techniques for the quantitative evaluation of the effects of three different pharmacotherapy protocols of chronic moderate adult asthma on hospital services (emergency room use and hospitalizations). The therapies compared were: (1) inhaled beta2-agonist agent and inhaled cromolyn; (2) inhaled beta2-agonist agent and an inhaled conticosteroid agent; (3) inhaled beta2-agonist agent and sustained-release theophylline. The combined therapy of an inhaled beta2-agonist agent and an inhaled corticosteroid agent had the lowest cost-effectiveness ratio of the three treatments indicating it should be the therapy of choice when associated hospital costs are included. Even though the inhaled beta2-agonist agent and sustained-release theophylline protocol had the lowest maintenance medication costs, it also had the highest cost-effectiveness ratio, suggesting it is the least desirable therapy when associated hospital services are included in the costs.

Descriptors :   *COST EFFECTIVENESS, *MARKOV PROCESSES, *PHARMACOLOGY, *PHARMACOLOGICAL ANTAGONISTS, *ASTHMA, TEST AND EVALUATION, MAINTENANCE, METHODOLOGY, RATIOS, STOCHASTIC PROCESSES, EMERGENCIES, MODELS, THESES, COSTS, MEDICINE, THERAPY, SPACE(ROOM), MEDICAL SERVICES, HOSPITALS, HEALTH CARE FACILITIES, HOSPITALIZATIONS, ADULTS, CORTICOSTEROID AGENTS.

Subject Categories : Medicine and Medical Research
      Economics and Cost Analysis
      Pharmacology

Distribution Statement : APPROVED FOR PUBLIC RELEASE