Accession Number : ADA307820

Title :   Early Detection of Breast Cancer on Mammograms Using: Perceptual Feedback, Computer Processed Images and Ultrasound.

Descriptive Note : Annual rept. 31 Dec 94-30 Dec 95,

Corporate Author : PENNSYLVANIA UNIV PHILADELPHIA

Personal Author(s) : Bloch, Peter

PDF Url : ADA307820

Report Date : JAN 1996

Pagination or Media Count : 163

Abstract : Several approaches for improving the detection of small tumors in the breast were explored. These included: (1) Perceptual feedback to decrease errors in missing tumors that are actually visible on the initial screening mammogram. The observers head-eye-position was recorded while viewing mammograms. It was found that false negative decisions in identifying a lesion was associated with prolong dwell time. Visual feedback, obtained by placing a small circle on the image surrounding the suspicious region (as predicted by the gaze duration), enhanced the detectability of masses. (2) Computer processing of screening mammograms for detection of clusters of microcalcifications and parenchyma patterns associated with developing lesions. Preserving the high spatial resolution and wide latitude in the digitized mammogram was found important for computer aided detection of subtle microcalcifications. Elevated mammography density has been associated with an increased risk of developing breast cancer. An algorithm was developed to perform quantification of the elevated parenchyma density on digitized mammograms. (3) High resolution ultrasound. The ultrasound distortion in the female breast image was identified and compensating algorithm developed to reduce the distortions. Design consideration was performed for two dimensional large acoustic transducers for high resolution breast imaging. The analysis indicates that using a 2D array would significantly increase the resolution of ultrasound mammography.

Descriptors :   *COMPUTER AIDED DESIGN, *HIGH RESOLUTION, *ULTRASONICS, *IMAGES, *MAMMARY GLANDS, *BREAST CANCER, ALGORITHMS, SPATIAL DISTRIBUTION, DENSITY, DETECTION, RISK, DECISION MAKING, COMPUTERS, PROCESSING, RESOLUTION, NEOPLASMS, CLUSTERING, FEEDBACK, VISION, COMPENSATION, DISTORTION, PERCEPTION, DWELL TIME, LESIONS, LATITUDE, CIRCLES, MAMMOGRAPHY.

Subject Categories : Medicine and Medical Research
      Cybernetics
      Optical Detection and Detectors

Distribution Statement : APPROVED FOR PUBLIC RELEASE