Accession Number : ADA310545

Title :   Detection and Characterization of Genetic Alterations on Chromosome 16 for Breast Cancer.

Descriptive Note : Final rept. 30 Sep 94-30 Jan 96,

Corporate Author : BETH ISRAEL HOSPITAL BOSTON MA

Personal Author(s) : Duda, Rosemary B.

PDF Url : ADA310545

Report Date : MAR 1996

Pagination or Media Count : 21

Abstract : This grant funded a Special Sabbatical for research in breast cancer for one year. There were two principle tasks in this grant; the first was to localize a potential tumor suppressor gene on chromosome 16 and the second was to further develop the molecular biology skills of the investigator. The research project continues to be in progress as we are at the stage of the secondary screening of a normal breast cell cDNA library and are preparing to sequence the DNA. In addition to this project, two additional studies were initiated, evaluating the effects of estrogen and progesterone on breast cancer cells.

Descriptors :   *DEOXYRIBONUCLEIC ACIDS, *CHROMOSOMES, *GENETICS, *MAMMARY GLANDS, *BREAST CANCER, DETECTION, CELLS, SECONDARY, NEOPLASMS, GENES, SUPPRESSORS, PROGESTERONE, ESTROGENS.

Subject Categories : Biochemistry
      Medicine and Medical Research

Distribution Statement : APPROVED FOR PUBLIC RELEASE