Accession Number : ADA311388

Title :   Phytoestrogens in the Food Supply.

Descriptive Note : Midterm rept. for 15 Mar 94-31 Dec 95,

Corporate Author : DEPARTMENT OF AGRICULTURE WASHINGTON DC

Personal Author(s) : Beecher, Gary R.

PDF Url : ADA311388

Report Date : JAN 1996

Pagination or Media Count : 26

Abstract : Endogenous estrogens are thought to have a role in the etiology of breast cancer. Several components of plant foods have estrogenic activity or are metabolized to active compounds by mammalian systems (phytoestrogens). The impact of these constituents on breast cancer risk is unknown because of the lack of databases containing appropriate values for foods. The goal of this research is to provide a database of values for the various isoflavones (one family of phytoestrogens) in soy-based foods and commodities. Six critical research components have been identified: (1) develop and validate rugged analytical procedures, (2) establish appropriate analytical quality control system, (3) identify commonly consumed soy-based foods and commodities, (4) develop food sampling scheme for each food or commodity, (5) prepare and analyze foods, and (6) develop critical data evaluation system and prepare database of values. Research components one through three have been completed. Several foods have been sampled, based on appropriate sampling schemes, prepared and analyzed. Additional foods will be sampled and analyzed as food sales information is received. The data evaluation system currently is being modified to accept and review isoflavone data. When all data have been entered into this system, a database of isoflavone values complete with food names and codes will be produced.

Descriptors :   *SOYBEANS, *ESTROGENS, *BREAST CANCER, DATA BASES, QUANTITATIVE ANALYSIS, METABOLISM, ETIOLOGY, QUALITY CONTROL, STATISTICAL ANALYSIS, MEDICAL RESEARCH, ANALYTICAL CHEMISTRY, COMMODITIES, METABOLITES, CHROMATOGRAPHIC ANALYSIS, FOOD CONSUMPTION, CARBOHYDRATE METABOLISM, CAROTENOIDS, PROTEIN METABOLISM.

Subject Categories : Biochemistry
      Medicine and Medical Research
      Food, Food Service and Nutrition

Distribution Statement : APPROVED FOR PUBLIC RELEASE