Accession Number : ADA311777

Title :   The Chemistry of Perfluoroisobutylene (PFIB) with Nitrone and Nitroso Spin Traps. An EPR/Spin Trapping Study.

Descriptive Note : Technical rept.,

Corporate Author : ARMY MEDICAL RESEARCH INST OF CHEMICAL DEFENSE ABERDEEN PROVING GROUND MD

Personal Author(s) : Arroyo, Carmen M.

PDF Url : ADA311777

Report Date : MAY 1996

Pagination or Media Count : 17

Abstract : Applying EPR/Spin Trapping techniques, several reactive intermediate species were identified in the reaction of perfluoroisobutylene (PFIB) with nitrone and nitroso spin trap agents: the carbon dioxide radical anion (CO2(-)), a carbonyl fluoride intermediate (COF), and vinyl carbanions of PFIB. The reaction of PFIB with N-t-butyl-alpha-phenylnitrone (PBN) forms a dipolar ion which undergoes electron transfer reactions generating stable nitrone spin adducts. Nitroso compounds reacted with carbanions derived from PFIB, which raises the possibility that electron transfer reactions of this type might account for the observed nitroxides. Our results suggest that PFIB undergoes some type of electron transfer reactions leading to several reactive intermediate species (RIS). The implications of these observations on pulmonary damage caused by inhalation of PFIB are discussed. p3

Descriptors :   *ELECTRON PARAMAGNETIC RESONANCE, *TRAPS, *SPIN STATES, *FLUORINE COMPOUNDS, *NITROSO COMPOUNDS, IONS, DAMAGE, REACTIVITIES, CHEMISTRY, CHEMICAL REACTIONS, DIPOLES, LUNG, BUTYL RADICALS, NITROGEN OXIDES, CARBON DIOXIDE, ELECTRON TRANSFER, PHENYL RADICALS, FLUORIDES, ANIONS, CARBONYL COMPOUNDS, INHALATION, OLEFIN POLYMERS.

Subject Categories : Polymer Chemistry
      Organic Chemistry
      Physical Chemistry
      Atomic and Molecular Physics and Spectroscopy

Distribution Statement : APPROVED FOR PUBLIC RELEASE