Accession Number : ADA313717

Title :   Genetic Engineering of Polymers Containing Non-Natural Amino Acids.

Descriptive Note : Final rept. 10 May 93-9 May 96,

Corporate Author : MASSACHUSETTS UNIV AMHERST DEPT OF POLYMER SCIENCE AND ENGINEERING

Personal Author(s) : Tirrell, David A.

PDF Url : ADA313717

Report Date : JUN 1996

Pagination or Media Count : 6

Abstract : The goal of this research program has been to establish strategies for producing protein-based materials that contain amino acids not normally found in natural proteins. Efforts have been focused on amino acids with fluorinated, electroactive or conformationally constrained side chains, and have allowed us to prepare protein-based polymers with unique properties, including low surface energies and sensitivity to electrochemical signals. These developments have expanded in a substantial way the range of materials properties accessible via chemical or biological synthesis of polypeptides and artificial proteins.

Descriptors :   *POLYMERS, *GENETIC ENGINEERING, *AMINO ACIDS, BIOLOGY, PEPTIDES, PROTEINS, SYNTHESIS(CHEMISTRY), ELECTROCHEMISTRY, SENSITIVITY, LOW ENERGY, SIGNALS, CHAINS, BIOSYNTHESIS, SURFACE ENERGY, ARTIFICIAL PRECIPITATION.

Subject Categories : Genetic Engineering and Molecular Biology
      Physical Chemistry
      Polymer Chemistry

Distribution Statement : APPROVED FOR PUBLIC RELEASE