Accession Number : ADA313747

Title :   X-Ray Crystallography of Botulinum Neurotoxins.

Descriptive Note : Final rept. 1 May 93-30 Apr 96,

Corporate Author : VETERANS ADMINISTRATION MEDICAL CENTER PITTSBURGH PA

Personal Author(s) : Sax, Martin

PDF Url : ADA313747

Report Date : MAY 1996

Pagination or Media Count : 8

Abstract : Botulinum neurotoxin E is understudy crystallographically. Preliminary crystal data have been collected and a heavy atom derivative search is in progress. The structural information is relevant for applications in the development of vaccines and in the improvement of therapeutic uses of the neurotoxin.

Descriptors :   *X RAYS, *CRYSTALLOGRAPHY, *CLOSTRIDIUM BOTULINUM, *NEUROTOXINS, CRYSTAL STRUCTURE, STRUCTURAL PROPERTIES, ATOMS, SEARCHING, TOXINS AND ANTITOXINS, VACCINES, BACTERIAL TOXINS, CNS DEPRESSANTS.

Subject Categories : Radiobiology
      Microbiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE