Accession Number : ADA313899

Title :   Research in Quantitative Bioassay Methodology and Risk Analysis and Characterization.

Corporate Author : NAVAL POSTGRADUATE SCHOOL MONTEREY CA DEPT OF OPERATIONS RESEARCH

Personal Author(s) : Gaver, Donald P. ; Jacobs, Patricia A.

PDF Url : ADA313899

Report Date : JUL 1996

Pagination or Media Count : 120

Abstract : The use of canonical correlation to combine information from biological testing systems is discussed. A graphical procedure to combine results from biological test systems is proposed. Results are presented of analyses of data from health screens to monitor the health status of medaka used in toxicological studies. A statistical model that incorporates a non-ignorable missing data mechanism is proposed to study the effect of leukocrit values which are not measurable. Results are presented of analyses of pathology data from the six month interim sacrifice of the West Branch Canal Creek Carcinogenicity Study with Medaka, Test 401-002R.

Descriptors :   *MATHEMATICAL MODELS, *CORRELATION, *STATISTICAL ANALYSIS, *CARCINOGENS, TEST AND EVALUATION, METHODOLOGY, QUANTITATIVE ANALYSIS, RISK, BIOLOGY, GRAPHICS, PATHOLOGY, STREAMS, CANALS, TOXICOLOGY, BIOASSAY.

Subject Categories : Numerical Mathematics

Distribution Statement : APPROVED FOR PUBLIC RELEASE