Accession Number : ADA315376

Title :   Mechanisms & Diagnostics of Ultrashort Pulse Laser Ocular Effects.

Descriptive Note : Final technical rept. 14 Apr 93-14 Apr 96,

Corporate Author : MASSACHUSETTS INST OF TECH CAMBRIDGE RESEARCH LAB OF ELECTRONICS

Personal Author(s) : Fujimoto, James G.

PDF Url : ADA315376

Report Date : 22 AUG 1996

Pagination or Media Count : 12

Abstract : The objective of our program has been to investigate the mechanisms of short and ultrashort pulse laser retinal injury and to develop and apply new diagnostics for the assessment of retinal injury. A key focus of our effort during this program has been to develop and apply optical coherence tomography (OCT) to investigate the morphology of retinal laser injury. OCT is a new noninvasive optical diagnostic technique for micron scale cross sectional imaging, which can permit the noninvasive imaging of retinal microstructure in situ. Working in collaboration with investigators at Brooks AFB, we have applied OCT to study lesion structure, development, and healing response from laser retinal injury. An increased understanding of the mechanisms of laser retinal injury is relevant to the - - development of laser safety standards as well as the development and improvement of clinical laser therapies for ocular disease.

Descriptors :   *OPTICAL PROPERTIES, *CLINICAL MEDICINE, *PULSED LASERS, *NONLINEAR OPTICS, *DIAGNOSIS(MEDICINE), *RETINA, MICROSTRUCTURE, COHERENCE, DISEASES, LASERS, RESPONSE, IMAGES, STANDARDS, THERAPY, WOUNDS AND INJURIES, EYE, LASER SAFETY, TOMOGRAPHY, LESIONS, HEALING.

Subject Categories : Anatomy and Physiology
      Lasers and Masers
      Optics

Distribution Statement : APPROVED FOR PUBLIC RELEASE