Accession Number : ADA317876

Title :   Nature and Prognostic Significance of Alterations in the DCC and E-Cadherin Genes in Breast Cancer.

Descriptive Note : Annual rept. 15 Jul 95-14 Jun 96,

Corporate Author : YALE UNIV NEW HAVEN CT

Personal Author(s) : Rimm, David L.

PDF Url : ADA317876

Report Date : AUG 1996

Pagination or Media Count : 77

Abstract : In the original application, three technical objectives were proposed with the goal of understanding the role of the adhesion molecules DCC and E-cadherin in breast cancer. The initial task focused on use of LOH to assist in confirming that these adhesion molecules are important in the pathogenesis of breast cancer. Ultimately, the long term goals were to apply the findings of these studies to improving the diagnosis and management of breast cancer.

Descriptors :   *GENES, *BREAST CANCER, MANAGEMENT, MOLECULES, ADHESION, DIAGNOSIS(MEDICINE), PATHOGENESIS.

Subject Categories : Biochemistry
      Genetic Engineering and Molecular Biology
      Medicine and Medical Research

Distribution Statement : APPROVED FOR PUBLIC RELEASE