Accession Number : ADA318678

Title :   Request for Nuclear Magnetic Resonance and X-Ray Crystallographic Instrumentation for North Carolina Central University.

Descriptive Note : Final rept. 1 Sep 95-31 Aug 96,

Corporate Author : NORTH CAROLINA CENTRAL UNIV DURHAM

Personal Author(s) : Izydore, Robert A.

PDF Url : ADA318678

Report Date : 26 NOV 1996

Pagination or Media Count : 4

Abstract : The purpose of the grant was to purchase a 300 MHz multinuclear nuclear magnetic resonance (NMR) spectrometer. The cost of the instrument was projected to be the funded amount of $243,058. Additionally it was projected $48, 950, was needed to renovate room 123 of the Hubbard Chemistry Building at North Carolina Central University (NCCU) to accommodate the instrument. The specific renovations needed were itemized in the proposal. The costs of the renovation was to be paid by NCCU as matching funds. The instrument is to be used by the principal investigator (PI) to characterize new drugs having antiinflammatory properties that he is synthesizing. These drugs include 3,5-isoxazolidinediones, 3,5- pyrazolidinediones, 1,3 ,5-triazabicyclo 3.1. 0hexane-2,4-diones, 1,3 ,5-triazine-4,6( 1H,5H)-diones and 1,2,4-triazolidine-3,5-diones. The instrument will be used by Dr. Shawn Sendlinger to characterize new inorganic oligomers and polymers having improved nonlinear properties. Other members of the Chemistry faculty will use the instrument to characterize their research compounds. The instrument will also be available to B.S. and M.S. students in the Department for their research projects, and it will be used in several of our teaching courses. Magnetic nuclei to be detected by the instrument include (1)H, (13)C, (15)N, (31)P, (51)V, (95)Mo, and other transition metals.

Descriptors :   *NUCLEAR MAGNETIC RESONANCE, *X RAYS, *DRUGS, *SPECTROMETERS, *CRYSTALLOGRAPHY, *ANTIINFLAMMATORY AGENTS, MAGNETIC PROPERTIES, TRANSITION METALS, POLYMERS, CHEMISTRY, NONLINEAR SYSTEMS, ORGANIC COMPOUNDS, INSTRUMENTATION, MATCHING, OLIGOMERS, NUCLEI, INORGANIC MATERIALS.

Subject Categories : Inorganic Chemistry
      Organic Chemistry
      Test Facilities, Equipment and Methods
      Crystallography
      Atomic and Molecular Physics and Spectroscopy

Distribution Statement : APPROVED FOR PUBLIC RELEASE