Accession Number : ADA319970

Title :   The Cloning of the BRCA1 Gene.

Descriptive Note : Annual rept. 1 Sep 95-31 Aug 96,

Corporate Author : MONTREAL GENERAL HOSPITAL (QUEBEC) RESEARCH INST

Personal Author(s) : Narod, Steven A.

PDF Url : ADA319970

Report Date : SEP 1996

Pagination or Media Count : 15

Abstract : The BRCA1 gene was cloned in 1994. Dr. Narod participated in this international effort. Dr. Narod has been active in characterizing the range and frequency of mutations in families with hereditary breast cancer and in Ashkenazi Jewish women with familial and sporadic cancer. By studying large numbers of BRCA1 carriers he has identified genetic and non-genetic risk modifiers and has helped evaluate the outcomes of genetic counselling of hereditary breast cancer patients.

Descriptors :   *GENETIC ENGINEERING, *BREAST CANCER, FREQUENCY, MUTATIONS, CLONES, GENETICS, COUNSELING.

Subject Categories : Medicine and Medical Research

Distribution Statement : APPROVED FOR PUBLIC RELEASE