Accession Number : ADA321702

Title :   Progress Report on Metabolism of Fission Products for Period Ending October 15, 1943,

Corporate Author : TECHNICAL INFORMATION SERVICE (AEC) OAK RIDGE TN

Personal Author(s) : Overstreet, Roy ; Jacobson, Louis ; Fisher, Harvey ; Scott, Kenneth ; Axelrod, Dorothy

PDF Url : ADA321702

Report Date : 15 OCT 1943

Pagination or Media Count : 52

Abstract : Unseparated Fission Products: Unseparated fission products have been isolated from 18 pounds of neutron bombarded UO2(NO3)2-6H2O free from carrier and containing less than .03 micrograms of Uranium per microcurie of activity. The final solution was assayed for its content of Strontium, Yttrium + Praseodymium, Zirconium, Columbium, Ruthenium, Tellurium, Cesium, Barium, Cerium, and UX1. Tracer studies were done on a large group of rats which received the prepared solution by intramuscular, intraperitoneal, intrapulmonary, and oral routes of administration. The time intervals ranged from one to sixty-four days. The skeleton was the chief point of deposition for the absorbed radioactive mixture for all four routes of administration. Considerable and prolonged retention occurred in the lungs following intrapulmonary administration. From 3 to 5% was absorbed from the digestive tract. Excretion was slow and the digestive tract was the chief channel of elimination. Approximately 50% of the activity was excreted over the sixty-four day period following intraperitoneal and intramuscular injection.

Descriptors :   *METABOLISM, *FISSION PRODUCTS, TIME INTERVALS, RATS, CESIUM, MIXTURES, DEPOSITION, SOLUTIONS(GENERAL), CERIUM, NIOBIUM, RADIOACTIVITY, ZIRCONIUM, ROUTING, PRASEODYMIUM, ELIMINATION, BARIUM, RUTHENIUM, STRONTIUM, CHANNELS, TELLURIUM, URANIUM, ORAL INTAKE, YTTRIUM, SKELETON, TRACER STUDIES, INGESTION(PHYSIOLOGY).

Subject Categories : Biochemistry
      Radioactiv, Radioactive Wastes & Fission Prod

Distribution Statement : APPROVED FOR PUBLIC RELEASE