Accession Number : ADA321819

Title :   Breast Cancer Tissue Repository.

Descriptive Note : Annual rept. 1 Sep 95-31 Aug 96,

Corporate Author : DUKE UNIV DURHAM NC

Personal Author(s) : Iglehart, J. D.

PDF Url : ADA321819

Report Date : SEP 1996

Pagination or Media Count : 8

Abstract : During the preceding year, the Duke Breast Cancer Tissue Repository collected breast cancer tissue from 126 patients undergoing surgery for a primary breast cancer. This compares to 124 entries in the first year of the repository. As before, nearly all of these tissues were both snap frozen in liquid nitrogen and embedded in gelatin for special applications. In 120 patients, serum and peripheral white cells were collected prior to surgery. An additional bank of normal plasma and white cells has been collected during the previous year. The Department of Defense Repository has provided tissues and blood to multiple investigators within Duke and in other U.S. institutions. The Repository has supported the Duke Specialized Project of Research Excellence (SPORE) and the Duke Comprehensive Cancer Center in a joint effort to establish a breast cancer genetics program at Duke. For this endeavor, the Repository has provided phlebotomy and blood storage for research studies looking at new genes and genetic loci in candidate families.

Descriptors :   *TISSUES(BIOLOGY), *STORAGE, *BREAST CANCER, HUMANS, CHROMOSOMES, GENES, LIQUID NITROGEN, BLOOD SERUM, GENETICS, LEUKOCYTES, MAMMARY GLANDS, BLOOD PLASMA, GELATINS, TISSUE BANKS, BLOOD STORAGE, HISTOLOGICAL TECHNIQUES, METASTASIS.

Subject Categories : Biochemistry
      Genetic Engineering and Molecular Biology
      Anatomy and Physiology
      Medicine and Medical Research
      Medical Facilities, Equipment and Supplies

Distribution Statement : APPROVED FOR PUBLIC RELEASE