Accession Number : ADA322219
Title : Cyclin E, a Potential Prognostic Marker in Breast Cancer.
Descriptive Note : Annual rept. 1 Oct 95-30 Sep 96,
Corporate Author : STATE UNIV OF NEW YORK AT ALBANY
Personal Author(s) : Keyomarsi, Khandan
PDF Url : ADA322219
Report Date : OCT 1996
Pagination or Media Count : 107
Abstract : Cyclins are prime cell cycle regulators and central to the control of cell proliferation in eukaryotic cells via their association with and activation of cyclin-dependent protein kinases. The overall purpose of this 4 year study is to use the altered expression of cyclin E as a diagnostic/prognostic marker and to investigate the mechanisms and repercussions of this alteration in breast cancer.
Descriptors : *PROTEINS, *CELLS(BIOLOGY), *DIAGNOSTIC AGENTS, *BREAST CANCER, ENZYMES, NEOPLASMS, CYCLES, DEOXYRIBONUCLEIC ACIDS, CYTOPLASM, CELL DIVISION, GROWTH SUBSTANCES, GROWTH(PHYSIOLOGY), PHOSPHORUS TRANSFERASES.
Subject Categories : Biochemistry
Anatomy and Physiology
Medicine and Medical Research
Distribution Statement : APPROVED FOR PUBLIC RELEASE