Accession Number : ADA322219

Title :   Cyclin E, a Potential Prognostic Marker in Breast Cancer.

Descriptive Note : Annual rept. 1 Oct 95-30 Sep 96,

Corporate Author : STATE UNIV OF NEW YORK AT ALBANY

Personal Author(s) : Keyomarsi, Khandan

PDF Url : ADA322219

Report Date : OCT 1996

Pagination or Media Count : 107

Abstract : Cyclins are prime cell cycle regulators and central to the control of cell proliferation in eukaryotic cells via their association with and activation of cyclin-dependent protein kinases. The overall purpose of this 4 year study is to use the altered expression of cyclin E as a diagnostic/prognostic marker and to investigate the mechanisms and repercussions of this alteration in breast cancer.

Descriptors :   *PROTEINS, *CELLS(BIOLOGY), *DIAGNOSTIC AGENTS, *BREAST CANCER, ENZYMES, NEOPLASMS, CYCLES, DEOXYRIBONUCLEIC ACIDS, CYTOPLASM, CELL DIVISION, GROWTH SUBSTANCES, GROWTH(PHYSIOLOGY), PHOSPHORUS TRANSFERASES.

Subject Categories : Biochemistry
      Anatomy and Physiology
      Medicine and Medical Research

Distribution Statement : APPROVED FOR PUBLIC RELEASE