Accession Number : ADA322444
Title : Linkage of Molecular and Epidemiological Breast Cancer Investigations with Treatment Data: A Specialized Registry.
Descriptive Note : Annual rept. 1 Oct 95-30 Sep 96,
Corporate Author : DARTMOUTH COLL HANOVER NH
Personal Author(s) : McIntyre, O. R.
PDF Url : ADA322444
Report Date : OCT 1996
Pagination or Media Count : 146
Abstract : During year two of this project, the Cancer and Leukemia Group B (CALGB) entered 40 breast cancer patients into the Linked Registry according to procedures specified in CALGB Protocol 9484. The telephone interviews of patients have gone smoothly and the entry of data from the interviews by the CALGB Data Management Center has been free of problems. The flow of patient samples from CALGB 9484 has begun and the storage of samples and preparation of DNA has been problem free. The number of institutions participating in the project has been limited by the actions of IRBs many of which have disapproved the protocol because of concerns about the risks of genetic testing. In view of this, the protocol has been amended in a manner that will reduce or eliminate concern about this issue and to improve the efficiency of patient entry. A Certificate of Confidentiality has been granted to this project further reducing the risk to patients contributing samples for studies of genomic DNA.
Descriptors : *MOLECULAR BIOLOGY, *DIRECTORIES, *EPIDEMIOLOGY, *BIOMEDICAL INFORMATION SYSTEMS, *BREAST CANCER, DATA BASES, TISSUES(BIOLOGY), DATA MANAGEMENT, DEOXYRIBONUCLEIC ACIDS, MUTATIONS, CHROMOSOMES, ETIOLOGY, SAMPLING, INFORMATION CENTERS, DATA STORAGE SYSTEMS, COMPUTER NETWORKS, PATIENTS, GENETICS, CHEMOTHERAPY, INTERVIEWING, LEUKEMIA.
Subject Categories : Genetic Engineering and Molecular Biology
Medicine and Medical Research
Distribution Statement : APPROVED FOR PUBLIC RELEASE