Accession Number : ADA323835

Title :   Inhibition of Olfactory Receptor Cells: An Aquatic Model.

Descriptive Note : Final progress rept. 15 Jan 93-31 Dec 95,

Corporate Author : FLORIDA UNIV ST AUGUSTINE WHITNEY LAB FOR EXPERIMENTAL MARINE BIOLOGY AND MED ICINE

Personal Author(s) : Ache, Barry W. ; Greenberg, Robert M.

PDF Url : ADA323835

Report Date : 07 APR 1997

Pagination or Media Count : 5

Abstract : CDNAs encoding two elements of the inositol phosphate-based intracellular signaling system were fully cloned and sequenced from the olfactory organ of the spiny lobster, an aquatic animal model for olfactory research. Antibody and molecular probes developed from these sequences are being used to study how this one of two olfactory signaling pathways is distributed across the ensemble of receptor cells that constitute the olfactory organ. The resulting insight into peripheral olfactory organization could improve the design of detector arrays in biosensors for odors and other chemical substances.

Descriptors :   *INHIBITION, *SENSE ORGANS, *CHEMORECEPTORS, *SMELL, IONS, PROBES, PROTEINS, DEOXYRIBONUCLEIC ACIDS, CODING, ANTIBODIES, MOLECULAR BIOLOGY, CLONES, RIBONUCLEIC ACIDS, ORGANIC PHOSPHORUS COMPOUNDS, AQUATIC ANIMALS, LOBSTER, NOSE(ANATOMY), ODORS.

Subject Categories : Biochemistry
      Genetic Engineering and Molecular Biology
      Biology
      Anatomy and Physiology
      Medicine and Medical Research

Distribution Statement : APPROVED FOR PUBLIC RELEASE