Accession Number : ADA324875

Title :   Real-Time Monitoring and Control Methodologies to Aid in the Study of Protein Interactions for Biosensor Applications.

Descriptive Note : Final progress rept.,

Corporate Author : TRUSTEES OF BOSTON UNIV MA

Personal Author(s) : Bestavros, Azer

PDF Url : ADA324875

Report Date : 01 MAR 1997

Pagination or Media Count : 13

Abstract : There is an emergent need for portable, inexpensive, reusable, and reliable sensors of environmental contaminants for both military and civilian uses. The development and study of such sensors is crucial for many applications. Among others, we mention measuring groundwater and waste water contamination, monitoring processes for agricultural and food products, and detecting soil contamination. In addition, such a technology is key to many medical procedures. The use of these sensors may be required on a continual and/or on a regular basis. In that respect, optically based sensors of protein interactions-such as those utilizing the optical phenomenon of Surface Plasmon Resonance (SPR)-show promise in producing sensory systems that are reusable, precise and portable for a range of applications. This proposal is to develop a computing platform to be used in the real-time monitoring, studying, and control of protein interactions. In particular, this platform allows the adaptive control of biosensor devices by integrating various data analysis and decision support modules, which could be used in a real-time fashion to control on-going experiments or synthesize and schedule new experiments in a distributed environment.

Descriptors :   *DATA PROCESSING, *WASTE WATER, *GROUND WATER, *CONTAMINANTS, *BIOLOGICAL DETECTION, *ENVIRONMENTAL PROTECTION, *FOOD PROCESSING, MEASUREMENT, METHODOLOGY, ADAPTIVE CONTROL SYSTEMS, ENVIRONMENTS, DETECTORS, MONITORING, REAL TIME, DISTRIBUTION, INTERACTIONS, PROTEINS, SURFACES, MEDICINE, RELIABILITY, SCHEDULING, RESONANCE, CONTAMINATION, FOOD, PLASMONS, SENSES(PHYSIOLOGY), DECISION SUPPORT SYSTEMS.

Subject Categories : Food, Food Service and Nutrition
      Miscellaneous Detection and Detectors
      Water Pollution and Control
      Environmental Health and Safety

Distribution Statement : APPROVED FOR PUBLIC RELEASE