Accession Number : ADA324898

Title :   Field Testing of Meningococcal Group B Vaccine and Oral Cholera Vaccine.

Descriptive Note : Final rept. 20 Sep 91-19 Jun 95,

Corporate Author : PAN AMERICAN HEALTH ORGANIZATION WASHINGTON DC

Personal Author(s) : Albornoz, Jorge T.

PDF Url : ADA324898

Report Date : OCT 1995

Pagination or Media Count : 274

Abstract : Frorn l987 to 1990, in the city of Iquique, Chile, efficacy tests were carried out on a group B anti-meningococcal vaccine, which had been prepared by a group headed by Dr. Wendell Zollinger in the W.R.A.I.R in Washington D.C. This study, as was informed in previous reports, showed a 51% efficacy for all age groups under study (1 to 21 years of age) In children of 1 to 4 years of age the vaccine provided no protection with an efficacy of -23% after 30 months of follow-up; but in the volunteers aged 5 to 21 the efficacy was found to be 7O% during that same period. These results, which are not by any means satisfactory, were promising and allowed investigation to be continued in the search for a more effective vaccine. For this reason, it was decided to keep the research laboratory in Iquigue going for the period 1991 through 1994.

Descriptors :   *INFECTIOUS DISEASES, *ORAL INTAKE, *VACCINES, *NEISSERIA MENINGITIDIS, *MENINGITIS, TEST AND EVALUATION, AGING(PHYSIOLOGY), FIELD TESTS, RESEARCH FACILITIES, LABORATORIES, CHILDREN, CHOLERA, CHILE.

Subject Categories : Medicine and Medical Research
      Microbiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE