Accession Number : ADA325570

Title :   Acute, Subchronic and Reproductive Toxicity of Quadricyclane Vapor on Sprague-Dawley Rats.

Descriptive Note : Final rept. Mar 95-Jun 96,

Corporate Author : MANTECH ENVIRONMENTAL TECHNOLOGY INC DAYTON OH

Personal Author(s) : Wolfe, R. E. ; Kinkead, E. R. ; Feldman, M. L. ; Leahy, H. F. ; Narayanan, L.

PDF Url : ADA325570

Report Date : AUG 1996

Pagination or Media Count : 48

Abstract : The U.S. Air Force is currently developing High Energy Density Matter (HEDM) for use in advanced rocket propellants to improve their performance. An HEDM of immediate interest is Quadricyclane. Assessments were performed to determine the inhalation toxicity of Quadricyclane vapor. An acute 4-h exposure of male Sprague-Dawley rats to 5mg Quadricyclane resulted in complete mortality.

Descriptors :   *RATS, *VAPORS, *TOXICITY, *ROCKET PROPELLANTS, AIR FORCE, TOXIC HAZARDS, MALES, EXPOSURE(PHYSIOLOGY), MORTALITY RATE, NEUROTRANSMITTERS, HISTOPATHOLOGY, INHALATION, REPRODUCTION(PHYSIOLOGY), BLOOD CHEMISTRY.

Subject Categories : Anatomy and Physiology
      Toxicology
      Rocket Propellants

Distribution Statement : APPROVED FOR PUBLIC RELEASE