Accession Number : ADA325731

Title :   Decision Modeling of Psychosocial and Clinical Factors in Assessing Treatment Alternatives for Lobular Carcinoma in Situ.

Descriptive Note : Final rept. 1 Aug 94-31 Jul 96,

Corporate Author : NEW YORK UNIV NY

Personal Author(s) : Jordan, Theresa J.

PDF Url : ADA325731

Report Date : AUG 1996

Pagination or Media Count : 68

Abstract : The present project was designed to utilize existing longitudinal databases documenting risk of invasive cancer associated with Lobular Carcinoma in situ (LCIS) as well as newly collected data on quality of life associated with treatment options, to develop decision models for the treatment of premenopausal women diagnosed with LCIS and otherwise benign biopsy findings. Treatment options consisted of preventive bilateral mastectomy versus 'watch and wait' with intensive screening. Analysis of a 22 year prospective, longitudinal database provided by the Connecticut Tumor Registry suggested that the risk of invasive cancer associated with LCIS might be significantly lower than has been suggested in retrospective studies of older data.

Descriptors :   *CLINICAL MEDICINE, *BREAST CANCER, DATA BASES, MATHEMATICAL MODELS, COMPUTERIZED SIMULATION, RISK, NEOPLASMS, PATHOLOGY, CONNECTICUT, WOMEN, BIOPSY.

Subject Categories : Medicine and Medical Research
      Operations Research
      Computer Programming and Software

Distribution Statement : APPROVED FOR PUBLIC RELEASE