Accession Number : ADA325800

Title :   Repetitive Molecular Exclusion Chromatography of PGBx on Sephadex LH-20.

Corporate Author : NAVAL AIR DEVELOPMENT CENTER WARMINSTER PA AIRCRAFT AND CREW SYSTEMS TECHNOLO GY DIRECTORATE

Personal Author(s) : Shmukler, H. W. ; Kwong, S. F. ; Feely, W. ; Zawryt, M. G. ; Polis, E.

PDF Url : ADA325800

Report Date : 02 OCT 1980

Pagination or Media Count : 16

Abstract : PGB sub x a mixture of oligomers of 15-keto PGB1, was subjected to repetitive MEC on Sephadex LH-20 in an attempt to separate and purify the active principle. The resulting fractions were analyzed and found still to be heterogeneous. Although the MEC technique did not resolve the PGB sub x complex, low molecular weight fractions were obtained that may be amenable to mass spectral analysis.

Descriptors :   *MOLECULAR PROPERTIES, *CHROMATOGRAPHY, MOLECULAR WEIGHT, PURIFICATION, SEPARATION, CHEMICAL ANALYSIS, OLIGOMERS, MASS SPECTRA, PHOSPHORYLATION.

Subject Categories : Biochemistry
      Atomic and Molecular Physics and Spectroscopy
      Polymer Chemistry

Distribution Statement : APPROVED FOR PUBLIC RELEASE