Accession Number : ADA326077

Title :   Genetic Epidemiology of in situ Breast Cancer.

Descriptive Note : Annual rept. 15 Nov 95-14 Nov 96,

Corporate Author : YALE UNIV NEW HAVEN CT

Personal Author(s) : Claus, Elizabeth B.

PDF Url : ADA326077

Report Date : DEC 1996

Pagination or Media Count : 19

Abstract : This four-year project will define risk factors associated with BCIS through the mechanism of a case/control study. The study population will include approximately 800 cases of female breast carcinoma in situ and 800 age-matched female controls selected from the population of the state of Connecticut. Ninety two percent of contacted eligible cases and 80% of contacted eligible controls have agreed to participate in telephone interviews which collect information concerning family history of cancer, pregnancy and menstrual history, hormone replacement therapy, oral contraceptive use, fertility drug use, as well as sociodemographic variables. In addition, a tissue repository consisting of paraffin-embedded tumor tissue collected from each of the cases will be formed.

Descriptors :   *GENETICS, *EPIDEMIOLOGY, *BREAST CANCER, HORMONES, RISK, HUMANS, NEOPLASMS, POPULATION, CASE STUDIES, HISTORY, REPLACEMENT, THERAPY, CONNECTICUT, PREGNANCY, FAMILIES(HUMAN), MAMMARY GLANDS, INTERVIEWING, TISSUE BANKS, MENSTRUATION, FERTILITY.

Subject Categories : Biochemistry
      Genetic Engineering and Molecular Biology
      Anatomy and Physiology
      Medicine and Medical Research

Distribution Statement : APPROVED FOR PUBLIC RELEASE