Accession Number : ADA327025
Title : Effects of Acute and Prolonged Millimeter Wave Radiation Exposure Upon Corneal Endothelial Morphology.
Descriptive Note : Final technical rept. Jan-Dec 89,
Corporate Author : TEXAS UNIV AT AUSTIN
Personal Author(s) : Farrar, Roger P. ; Diller, Kenneth R. ; Rylander, H. G.
PDF Url : ADA327025
Report Date : JUN 1990
Pagination or Media Count : 151
Abstract : The purpose of this research was determine the injury threshold to the endothelium of the eye upon exposure to 35 GHz microwave radiation. The criterion for injury was defined as a statistically significant increase in mean cell area of the endothelial cell of the cornea. The experiments were conducted at the microwave radiation facility at Brooks AFB, TX. Four cats were each exposed to 10 mW/cm2 for 2 hours/day on alternative days, over a period of 2 weeks, for a total of 6 exposures per cat (12 hours of total exposure per cat). When the digitized images of the endothelial cells, obtained by noncontact specular microscopy, were examined and compared to that of control cats, no change in mean cell area of the endothelium of the exposed eye was detected. Four additional cats were exposed to 100 mW/cm2 for 2 hours per day on alternative days over a period of 2 weeks for a total of 12 hours of exposure per cat. In a like manner the digitized images of the endothelial cells were compared to those of control cats. No changes in the mean cell size of the endothelial cells were detected, either inunediately or up to 2 weeks after the last exposure. The original protocol was to increase the energy deposition to the eye to 500 and 1000 mW/cm2 and subsequently determine the threshold of damage to the endothelium of the eye. We were unable to increase the energy deposition to the cat because a focusing lens for the microwave generator is still being developed for the radiofrequency (RF) facility at Brooks Air Force Base. The dosimetry conducted on site indicated that the cats would receive too much overall RF radiation to allow us to attribute damage to the endothelium of the eye solely to the microwave effects upon the cornea. Therefore, the threshold of damage to the endothelium of the cornea induced by RF radiation, as evaluated by change in mean cell area of the endothe
Descriptors : *MILLIMETER WAVES, *WOUNDS AND INJURIES, *EYE, *THRESHOLDS(PHYSIOLOGY), *ENDOTHELIUM, *CORNEA, CONTROL, DIGITAL SYSTEMS, RADIATION, SIZES(DIMENSIONS), MORPHOLOGY, ENERGY, MICROWAVE EQUIPMENT, MICROSCOPY, DEPOSITION, IMAGES, FOCUSING, AIR FORCE FACILITIES, MEAN, EXPOSURE(PHYSIOLOGY), GENERATORS, CELLS(BIOLOGY), RADIOFREQUENCY, LENSES, SPECULAR REFLECTION, DOSIMETRY, CATS.
Subject Categories : Anatomy and Physiology
Distribution Statement : APPROVED FOR PUBLIC RELEASE