Accession Number : ADA327154

Title :   Fellowship to Study the Involvement of Heat Shock Proteins in Drug Resistance in Human Breast Cancer.

Descriptive Note : Annual rept. 30 Jan 96-29 Jan 97,

Corporate Author : TEXAS UNIV HEALTH SCIENCE CENTER AT SANANTONIO

Personal Author(s) : Fuqua, Suzanne A.

PDF Url : ADA327154

Report Date : MAR 1997

Pagination or Media Count : 17

Abstract : Heat shock proteins (hsps) are induced in cells in response to environmental stresses. It has been shown that some breast cancer patients express high levels of hsp27, which may augment the aggressiveness of these tumors and make them more resistant to treatment. The research funded by this fellowship is directed at understanding the regulation of hsp27 toward the development of a useful therapy for inhibiting breast cancer progression.

Descriptors :   *SHOCK, *DRUGS, *HEAT STRESS(PHYSIOLOGY), *BREAST CANCER, ENVIRONMENTS, HUMANS, PROTEINS, NEOPLASMS, RESPONSE, THERAPY, PATIENTS, RESISTANCE(BIOLOGY), PEPTIDE HYDROLASES, METASTASIS.

Subject Categories : Biochemistry
      Medicine and Medical Research
      Stress Physiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE