Accession Number : ADA328324

Title :   Repletion of Zinc and Iron Deficiencies Improves Cognition of Premenopausal Women.

Descriptive Note : Annual rept. 22 Sep 95-21 Sep 96,

Corporate Author : TEXAS UNIV AT GALVESTON

Personal Author(s) : Sandstead, Harold H.

PDF Url : ADA328324

Report Date : OCT 1996

Pagination or Media Count : 121

Abstract : This project investigates the relationship of zinc and iron nutriture to human neuropsychological function. Purpose: This project tests the hypothesis: 'Repletion of mild zinc and iron deficiencies will improve neuropsychological (neuromotor and cognitive) functions of premenopausal women.' The project has three major components: Women at risk of mild Zn and Fe deficiencies are identified through food frequency histories. This approach was effective in a previous project that measured the relation between zinc and iron nutriture of young women (1) The zinc and iron status of the subjects are characterized by techniques (zinc kinetics, serum ferritin, hemoglobin and red blood cell indices) that were effective in a previous project that measured the relation between zinc and iron nutriture of young women (1) Changes in neuropsychological function after zinc and iron repletion are measured by computerized neuropsychological tasks (adapted by Co-Investigator Penland) using a double- blind randomized controlled treatment cross-over design, with deficient and normal control groups. Our previous findings provided the basis for this project (2-5).

Descriptors :   *IRON, *DEFICIENCIES, *ZINC, *WOMEN, FUNCTIONS, COGNITION, METABOLISM, NUTRIENTS, HUMAN BODY, LOSSES, HYPOTHESES, NEUROLOGY, PSYCHOLOGY, ELIMINATION, BODY WEIGHT, EXCRETION, CREATININE.

Subject Categories : Pharmacology

Distribution Statement : APPROVED FOR PUBLIC RELEASE