Accession Number : ADA328384

Title :   Protective Immunity to Hepatitis B and Streptococcus Pneumoniae in Active Duty Women Versus Men: Prevalence and Response to Preventive Immunization.

Descriptive Note : Annual rept. 1 Dec 94-1 Aug 95,

Corporate Author : WALTER REED ARMY MEDICAL CENTER WASHINGTON DC

Personal Author(s) : Engler, Renata J.

PDF Url : ADA328384

Report Date : 30 SEP 1995

Pagination or Media Count : 8

Abstract : Women in the military may have an increased occupational of hepatitis B infection. There is currently on clear data available regarding differences in duration of vaccine response between men and women. This study will provide data regarding the prevalence of protective immunity among active duty women in different age groups, under the current guidelines of immunization practice. In addition, a cost-effective vaccine booster strategy will be compared to the standard 1.0 ml dose of vaccine. Since pneumonia among military recruits is caused by S. pneumoniae, data on the prevalence of natural immunity in active duty women would be helpful for future planning of more effective immunization strategies. Using a health assessment questionnaire, serum samples and anergy skin testing, subjects will be screened for eligibility and assessed to determine protective antibody levels to hepatitis B and S: pneumoniae. We suspect there is a difference-between women and men in antibody response from immunization to hepatitis B and natural immunity to S. pneumonise.

Descriptors :   *IMMUNITY, *HEPATITIS, *STREPTOCOCCUS, *PNEUMONIA, MILITARY PERSONNEL, HEALTH, ACTIVE DUTY, ANTIBODIES, BLOOD SERUM, WOMEN, PREVENTION, QUESTIONNAIRES, IMMUNIZATION, VACCINES.

Subject Categories : Biochemistry
      Medicine and Medical Research
      Pharmacology

Distribution Statement : APPROVED FOR PUBLIC RELEASE