Accession Number : ADA334113
Title : Treatment of Retinal Injuries by Low-Energy Laser; Models of Neurodegeneration in Retinal Injuries and Treatment by Low Energy Laser.
Descriptive Note : Rept. for 25 Mar 96-24 Sep 97,
Corporate Author : WEIZMANN INST OF SCIENCE REHOVOT (ISRAEL)
Personal Author(s) : Sxhwartz, Michal
PDF Url : ADA334113
Report Date : OCT 1997
Pagination or Media Count : 18
Abstract : We have demonstrated in previous studies that low energy laser reduces injury-induced deficits caused by acute partial injury of the rat optic nerve. The results of in-depth analysis suggest that the laser effect in this model is of a neuroprotective nature. We have devoted the time lapsed since approval of funding of the present study to characterization of the optic nerve partial lesion model, in an attempt to determine whether the progressive degeneration which occurs subsequently to the primary insult and continues in the absence of any external insult, is of a self-perpetuating nature, and whether such progressive degeneration follows any topographical pattern and whether any such pattern might be a reflection of the severity of the primary injury itself. By clarify the above points, we may turn our model into an ideal model for studying the neuroprotection of the optic nerve and retinal ganglion cells from injurious conditions.
Descriptors : *LASERS, *LOW ENERGY, *WOUNDS AND INJURIES, *RETINA, *MEDICAL RESEARCH, AGING(PHYSIOLOGY), TOPOGRAPHY, DEFICIENCIES, NERVE CELLS, CELLS(BIOLOGY), SALINE SOLUTION, OPTIC NERVE, GANGLIA.
Subject Categories : Anatomy and Physiology
Medicine and Medical Research
Distribution Statement : APPROVED FOR PUBLIC RELEASE