Accession Number : ADA335315
Title : Tuning Biphenyl Dioxygenase for Extended Substrate Specificity and Enhanced Activity
Descriptive Note : Final rept 1 May 96-30 Sep 97
Corporate Author : CALIFORNIA UNIV RIVERSIDE COLL OF ENGINEERING
Personal Author(s) : Chen, Wilfred
PDF Url : ADA335315
Report Date : 30 SEP 1997
Pagination or Media Count : 5
Abstract : At the time when public concern about PCBs contamination in the environment is increasing, there is also an increasing interest in the development of novel biodegradation processes that can rapidly and effectively remove PCB's. However, some of the PCB congeners are known to be very resistant to aerobic biodegradation, particularly in the initial attack by the biphenyl dioxygenases. We seek to broaden the substrate specificity of biphenyl dioxygenase from Pseudomonas sp.
Descriptors : *BIODEGRADATION, *AEROBIC PROCESSES, *POLYCHLORINATED BIPHENYLS, SUBSTRATES, DEOXYRIBONUCLEIC ACIDS, OXYGEN, AROMATIC HYDROCARBONS, CONTAMINATION, PSEUDOMONAS.
Subject Categories : Biochemistry
Genetic Engineering and Molecular Biology
Solid Wastes Pollution and Control
Distribution Statement : APPROVED FOR PUBLIC RELEASE