Accession Number : ADA335985

Title :   A Dedicated PET Scanner for Axillary Node Imaging

Descriptive Note : Annual rept 1 Sep 96-31 Aug 97

Corporate Author : CALIFORNIA UNIV LOS ANGELES

Personal Author(s) : Cherry, Simon

PDF Url : ADA335985

Report Date : SEP 1997

Pagination or Media Count : 14

Abstract : A key prognostic factor in breast cancer is the involvement of the axillary lymph nodes. This is currently determined by axillary lymph node dissection (ALND), a low yield surgical procedure associated with significant cost and morbidity. Positron emission tomography (PET), using F-18-fluorodeoxyglucose (FDG) tracer is a sensitive and non-invasive test for lymph node involvement and can be a cost-effective alternative to ALND. In this grant, we are developing a low cost, high performance dedicated PET camera for imaging the axillary nodes. This report summarizes the proposed design for the PET camera based on extensive simulation and benchtop detector measurements. The system will consist of two rectangular gamma-ray detectors operated in coincidence, using the new scintillator LSO and is projected to have significantly improved resolution and sensitivity compared with regular clinical PET scanners.

Descriptors :   *IMAGES, *SCANNERS, *LYMPH NODES, *BREAST CANCER, IMAGE PROCESSING, SIMULATION, DETECTORS, GAMMA RAYS, TOMOGRAPHY, GLUCOSE, LABELED SUBSTANCES, TRACER STUDIES, POSITRONS.

Subject Categories : Medicine and Medical Research
      Isotopes
      Nuclear Physics & Elementary Particle Physics

Distribution Statement : APPROVED FOR PUBLIC RELEASE