Accession Number : ADA336534

Title :   The Effects of a Comprehensive Coping Strategy on Clinical Outcomes in Breast Cancer Bone Marrow Transplant Patients and Primary Caregiver.

Descriptive Note : Annual rept. 1 Sep 96-31 Aug 97,

Corporate Author : JOHNS HOPKINS UNIV BALTIMORE MD

Personal Author(s) : Gaston-Johannson, Fannie

PDF Url : ADA336534

Report Date : AUG 1997

Pagination or Media Count : 92

Abstract : The purpose of this 4 year study is to determine the effects of the Comprehensive Coping Strategy Program (CCSP) on clinical outcomes and quality of life in breast cancer patients and their primary caregivers. Specifically, the purpose of this study was to compare descriptions of pain, psychological distress, fatigue, and perceived health status and burden of care in breast cancer patients who received autologous bone marrow transplant (ABMT) and their primary caregivers (PCGs) and participated in a CCSP and ABMT breast cancer patients and their PCGs who did not receive the CCSP. A randomized controlled clinical trial design was used Thus far, 110 patients and 85 primary caregivers have entered the study. Data are presented on 100 patients and 83 PCGs. Fifty patients were randomly assigned to the CCSP treatment group and 45 to the control group. The ABMT was canceled in 5 patients before baseline data were collected but after the consent from had been signed. Data were collected 20 days before hospitalization (baseline), during hospitalization (7 days after the ABMT), and again during the post hospitalization period which was 6 months to a year following the ABMT. The results showed trends that support the use of the CCSP in the reduction of psychological distress, improving the mental health status of the patient and increasing the number of hours of sleep. The CCSP group was able to avoid catastrophizing to a higher degree than the control group and reported a higher perception of health than the control group. Quality of life was improved in the psychological/spiritual domain within the treatment group. The treatment group showed an overall improvement in QOL of 10 points (p<0.001). The control group showed a smaller (6.8 points) improvement in QOL that was also significant (0.05).

Descriptors :   *CASE STUDIES, *PATIENTS, *BONE MARROW, *SURGICAL TRANSPLANTATION, STRESS(PSYCHOLOGY), CLINICAL MEDICINE, BASE LINES, MENTAL HEALTH, THRESHOLDS(PHYSIOLOGY), LIVING STANDARDS, BREAST CANCER, HEALTH CARE MANAGEMENT.

Subject Categories : Anatomy and Physiology
      Medicine and Medical Research

Distribution Statement : APPROVED FOR PUBLIC RELEASE