Accession Number : ADA336540

Title :   Risk Factors for Osteoporosis and Oral Bone Loss in Postmenopausal Women.

Descriptive Note : Annual rept. 16 Sep 96-15 Sep 97,

Corporate Author : STATE UNIV OF NEW YORK AT BUFFALO AMHERST

Personal Author(s) : Wacawski-Wende, Jean

PDF Url : ADA336540

Report Date : OCT 1997

Pagination or Media Count : 22

Abstract : The overall purpose of this study is to determine the relationship between skeletal and oral bone density, identify factors influencing bone loss, and determine the relationship between osteoporosis and oral bone loss, periodontal disease and tooth loss. We hypothesize that reduction in bone density leading to osteoporosis, plays a significant role in increasing susceptibility to destructive periodontitis and tooth loss. Sensitive and accurate measures of skeletal and oral bone mineral density, periodontal disease and tooth loss will be used, A wide variety of other risk factors for both osteopenia and periodontal disease will be assessed. A total of 1300 subjects are being recruited from an ongoing NIH funded study cohort, the Women's Health Initiative (WHI). Preliminary research findings from our pilot study determined that bone loss in the hip or spine is strongly associated bone loss in the jaw. Also, that bone loss in the hip was associated with tooth loss even when controlling for factors such as age, menopause, estrogen use, body mass and smoking. We have just completed year one of a four year study. Data collection will continue into year-4, as such, findings are not yet available to report.

Descriptors :   *LOSSES, *LOW DENSITY, *BONES, *ORAL DISEASES, *OSTEOPOROSIS, EXPERIMENTAL DATA, DATA ACQUISITION, PILOT STUDIES, WOMEN, PREVENTIVE DENTISTRY, ESTROGENS.

Subject Categories : Biology
      Anatomy and Physiology
      Medicine and Medical Research

Distribution Statement : APPROVED FOR PUBLIC RELEASE