Accession Number : ADA336663
Title : The Effect of a Moderate Aerobic Exercise Training Program on Ovarian Function.
Descriptive Note : Annual rept. 1 Sep 96-31 Aug 97
Corporate Author : UNIVERSITY OF SOUTHERN CALIFORNIA LOS ANGELES
Personal Author(s) : Shames, Lisa S.
PDF Url : ADA336663
Report Date : SEP 1997
Pagination or Media Count : 15
Abstract : There is substantial evidence to suggest that estrogens play a key role in the etiology of breast cancer. Both cross-sectional studies of highly trained athletes and prospective studies of high intensity exercise training programs have found a higher frequency of anovulation, lower levels of estradiol and in some cases a shortened luteal phase length with associated lower estradiol levels among these women. However, little is known about the effects of moderate intensity exercise on ovarian function. We hypothesize that the observed reduction in risk with exercise is due to altered ovarian function. We are investigating the relationship between a moderate intensity exercise training program and ovarian function. Specifically we aim: (1) to determine whether changes occur in frequency of ovulation as a result of a 6 month exercise training program, (2) to determine whether changes occur in serum E2 levels in ovulatory and anovulatory cycles in these women, and (3) to determine the luteal phase menstrual cycle lengths of these women as a result of the training program. We are collecting blood and urine specimens and questionnaire data (over a three year period) from 120 premenopausal women. We expect to have completed data and preliminary findings on 39 women by December 1997.
Descriptors : *AEROBIC PROCESSES, *EXERCISE(PHYSIOLOGY), *MENSTRUATION, *ESTROGENS, *OVARIES, FREQUENCY, FUNCTIONS, HORMONES, TRAINING, INTENSITY, LENGTH, ETIOLOGY, CROSS SECTIONS, LOW LEVEL, WOMEN, QUESTIONNAIRES, URINE, OVULATION, BREAST CANCER.
Subject Categories : Anatomy and Physiology
Distribution Statement : APPROVED FOR PUBLIC RELEASE